| Number | 685 |
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| Year | 1989 |
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| Drawer | 12 |
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| Entry Date | 11/15/1999 |
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| Authors | Gracco, C., & Kahane, J. C. |
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| Contact | |
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| Publication | Journal of Voice, 3(3), 204-212. |
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| Abstract | Age-related changes were investigated in the human vestibular folds of the larynx. Twelve male Caucasian larynges were obtained from autopsy and studied via light microscopy. The donors were free from head-neck pathologies or laryngeal trauma. Specimens included a 6-week-old infant, and at least one each from the second through eighth decades. Each specimen was decalcified and prepared for paraffin embedding and subsequent sectioning in the coronal plane at 6 μm. Sections were stained alternatively with safron-phloxine-hematoxylin and iron gallien elastic stains. Descriptive and quantitative data were obtained from light microscopy and planar morphometry using a computer image analysis system. Tissue changes included fatty infiltration of serous and mucous glands, fibrotic changes in connective tissue, and alterations in the distribution of mixed glands specific to serous/mucous ratios. Potential implications of findings to vocal function are discussed. |
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